The 4 DNA Bases and Their Strict Pairing Rules - Biology Wise The 4 DNA Bases and Their Strict Pairing Rules The DNA of all the living beings is composed of just four bases i.e. Adenine (A), Thymine (T), Guanine (G), and Cytosine (C). The various juxtapositions of these 4 bases give rise to the genetic codes of all the biota on the planet. Know more about these DNA bases in this post.